League Points Table
| Team Name | Played | Won | Drawn | Loss | Goals Scored | Goals Against | Goals Avg | Goals +/- | Points |
| Dominoes | 9 | 8 | 0 | 1 | 483 | 358 | 1.35 | 125 | 42 |
| Trafford Seniors | 9 | 7 | 0 | 2 | 430 | 320 | 1.34 | 110 | 38 |
| Lindal NC | 9 | 7 | 0 | 2 | 309 | 287 | 1.08 | 22 | 37 |
| Tameside*** | 9 | 7 | 0 | 2 | 449 | 316 | 1.42 | 133 | 36 |
| Beechwood NC | 8 | 4 | 0 | 4 | 327 | 274 | 1.19 | 53 | 26 |
| City of Manchester NC | 9 | 4 | 0 | 5 | 343 | 409 | 0.84 | -66 | 24 |
| Boughton Belles | 9 | 3 | 0 | 6 | 424 | 440 | 0.96 | -16 | 23 |
| Warrington Seniors | 9 | 3 | 0 | 6 | 298 | 348 | 0.86 | -50 | 21 |
| Manchester Fury | 8 | 1 | 0 | 7 | 268 | 413 | 0.65 | -145 | 10 |
| Ribble Valley*** | 9 | 0 | 0 | 9 | 268 | 434 | 0.62 | -166 | 6 |
***Penalties Applied - Please see Results Table
| Home Team | Score | | Score | Away Team |
| 10 October 2021 |
| Beechwood NC | 57 |
v
| 29 | City of Manchester NC |
| Boughton Belles | 59 |
v
| 37 | Manchester Fury |
| Dominoes | 53 |
v
| 54 | Tameside |
| Lindal NC | 47 |
v
| 19 | Ribble Valley |
| Trafford Seniors | 36 |
v
| 29 | Warrington Seniors |
| 24 October 2021 |
| Ribble Valley | 42 |
v
| 51 | Boughton Belles |
| Tameside | 40 |
v
| 34 | Beechwood NC |
| Warrington Seniors | 35 |
v
| 47 | Lindal NC |
| 31 October 2021 |
| Dominoes | 51 |
v
| 36 | Manchester Fury |
| Trafford Seniors | 52 |
v
| 43 | City of Manchester NC |
| Warrington Seniors | |
v
| | Ribble Valley |
| 14 November 2021 |
| Boughton Belles | 49 |
v
| 63 | Dominoes |
| City of Manchester NC | 22 |
v
| 33 | Lindal NC |
| Manchester Fury | |
v
| | Beechwood NC |
| Tameside | 38 |
v
| 43 | Trafford Seniors |
| 28 November 2021 |
| Beechwood NC | 50 |
v
| 43 | Boughton Belles |
| Lindal NC | |
v
| | Tameside |
| Warrington Seniors | 40 |
v
| 54 | City of Manchester NC |
| 12 December 2021 |
| Manchester Fury | 26 |
v
| 66 | Trafford Seniors |
| Ribble Valley | 43 |
v
| 62 | Dominoes |
| Tameside | 49 |
v
| 38 | Warrington Seniors |
| 09 January 2022 |
| Beechwood NC | 33 |
v
| 42 | Dominoes |
| City of Manchester NC | 41 |
v
| 32 | Ribble Valley |
| Lindal NC | 39 |
v
| 28 | Manchester Fury |
| Trafford Seniors | 60 |
v
| 33 | Boughton Belles |
| 23 January 2022 |
| Boughton Belles | 38 |
v
| 42 | Lindal NC |
| Manchester Fury | 31 |
v
| 47 | Warrington Seniors |
| Ribble Valley | 25 |
v
| 46 | Beechwood NC |
| Tameside | 74 |
v
| 33 | City of Manchester NC |
| 30 January 2022 |
| Tameside | 68 |
v
| 30 | Ribble Valley |
| Trafford Seniors | 36 |
v
| 52 | Dominoes |
| Warrington Seniors | 42 |
v
| 57 | Boughton Belles |
| 06 February 2022 |
| Beechwood NC | 31 |
v
| 33 | Trafford Seniors |
| Dominoes | 63 |
v
| 32 | Lindal NC |
| Manchester Fury | 33 |
v
| 44 | City of Manchester NC |
| 20 February 2022 |
| City of Manchester NC | 38 |
v
| 36 | Boughton Belles |
| Lindal NC | 31 |
v
| 47 | Beechwood NC |
| Tameside | 60 |
v
| 27 | Manchester Fury |
| Warrington Seniors | 36 |
v
| 45 | Dominoes |
| 06 March 2022 |
| Beechwood NC | 29 |
v
| 31 | Warrington Seniors |
| Boughton Belles | 58 |
v
| 66 | Tameside |
| Ribble Valley | 30 |
v
| 69 | Trafford Seniors |
| 20 March 2022 |
| City of Manchester NC | 39 |
v
| 52 | Dominoes |
| Lindal NC | 38 |
v
| 35 | Trafford Seniors |
| Manchester Fury | 50 |
v
| 47 | Ribble Valley |
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Penalties - Hover over icons for more information
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