League Points Table
| Team Name | Played | Won | Drawn | Loss | Goals Scored | Goals Against | Goals Avg | Goals +/- | Points |
| DB3 | 16 | 16 | 0 | 0 | 525 | 220 | 2.39 | 305 | 80 |
| Tyldesley Tigers | 16 | 12 | 1 | 3 | 402 | 263 | 1.53 | 139 | 64 |
| YPS | 16 | 11 | 0 | 5 | 409 | 343 | 1.19 | 66 | 58 |
| Rivington Mavs A | 16 | 10 | 1 | 5 | 449 | 372 | 1.21 | 77 | 57 |
| Thunderbolts | 16 | 6 | 2 | 8 | 343 | 358 | 0.96 | -15 | 40 |
| Smithills Sports Centre | 16 | 6 | 0 | 10 | 313 | 386 | 0.81 | -73 | 35 |
| Tyldesley Ladies NC | 16 | 6 | 0 | 10 | 278 | 372 | 0.75 | -94 | 35 |
| Tyldesley Tornadoes | 16 | 3 | 0 | 13 | 361 | 465 | 0.78 | -104 | 25 |
| The Saints | 16 | 0 | 0 | 16 | 186 | 487 | 0.38 | -301 | 5 |
***Penalties Applied - Please see Results Table
| Home Team | Score | | Score | Away Team |
| 07 September 2021 |
| DB3 | 33 |
v
| 15 | YPS |
| Rivington Mavs A | 32 |
v
| 25 | Tyldesley Tornadoes |
| Smithills Sports Centre | 14 |
v
| 29 | Tyldesley Tigers |
| The Saints | 13 |
v
| 24 | Tyldesley Ladies NC |
| 14 September 2021 |
| Tyldesley Ladies NC | 22 |
v
| 27 | Rivington Mavs A |
| Tyldesley Tigers | 17 |
v
| 29 | DB3 |
| YPS | 30 |
v
| 13 | Tyldesley Tornadoes |
| 15 September 2021 |
| Thunderbolts | 32 |
v
| 14 | The Saints |
| 21 September 2021 |
| DB3 | 38 |
v
| 10 | Tyldesley Ladies NC |
| Tyldesley Tornadoes | 11 |
v
| 37 | Tyldesley Tigers |
| 22 September 2021 |
| The Saints | 17 |
v
| 27 | YPS |
| Thunderbolts | 29 |
v
| 21 | Smithills Sports Centre |
| 28 September 2021 |
| Tyldesley Tornadoes | 26 |
v
| 27 | Tyldesley Ladies NC |
| YPS | 22 |
v
| 29 | Tyldesley Tigers |
| 29 September 2021 |
| Rivington Mavs A | 25 |
v
| 25 | Thunderbolts |
| The Saints | 13 |
v
| 28 | Smithills Sports Centre |
| 05 October 2021 |
| Rivington Mavs A | 16 |
v
| 42 | DB3 |
| Tyldesley Ladies NC | 22 |
v
| 28 | Thunderbolts |
| Tyldesley Tigers | 50 |
v
| 8 | The Saints |
| Tyldesley Tornadoes | 19 |
v
| 23 | Smithills Sports Centre |
| 12 October 2021 |
| DB3 | 40 |
v
| 8 | The Saints |
| Smithills Sports Centre | 13 |
v
| 32 | Rivington Mavs A |
| Tyldesley Ladies NC | 20 |
v
| 37 | YPS |
| 13 October 2021 |
| Thunderbolts | 31 |
v
| 18 | Tyldesley Tornadoes |
| 19 October 2021 |
| Smithills Sports Centre | 17 |
v
| 38 | DB3 |
| Tyldesley Tornadoes | 32 |
v
| 11 | The Saints |
| YPS | 36 |
v
| 35 | Rivington Mavs A |
| 20 October 2021 |
| Tyldesley Tigers | 31 |
v
| 9 | Thunderbolts |
| 02 November 2021 |
| DB3 | 34 |
v
| 15 | Tyldesley Tornadoes |
| Rivington Mavs A | 19 |
v
| 23 | Tyldesley Tigers |
| Smithills Sports Centre | 20 |
v
| 21 | Tyldesley Ladies NC |
| 03 November 2021 |
| Thunderbolts | 0 |
v
| 5 | YPS |
| 09 November 2021 |
| DB3 | 28 |
v
| 12 | Thunderbolts |
| The Saints | 20 |
v
| 34 | Rivington Mavs A |
| YPS | 28 |
v
| 22 | Smithills Sports Centre |
| 10 November 2021 |
| Tyldesley Tigers | 40 |
v
| 14 | Tyldesley Ladies NC |
| 16 November 2021 |
| Tyldesley Ladies NC | 23 |
v
| 14 | The Saints |
| Tyldesley Tigers | 38 |
v
| 19 | Smithills Sports Centre |
| Tyldesley Tornadoes | 27 |
v
| 43 | Rivington Mavs A |
| YPS | 8 |
v
| 31 | DB3 |
| 23 November 2021 |
| DB3 | 30 |
v
| 11 | Tyldesley Tigers |
| Rivington Mavs A | 37 |
v
| 21 | Tyldesley Ladies NC |
| Tyldesley Tornadoes | 19 |
v
| 31 | YPS |
| 24 November 2021 |
| The Saints | 5 |
v
| 23 | Thunderbolts |
| 30 November 2021 |
| Tyldesley Ladies NC | 0 |
v
| 5 | DB3 |
| Tyldesley Tigers | 32 |
v
| 29 | Tyldesley Tornadoes |
| 01 December 2021 |
| Smithills Sports Centre | 33 |
v
| 14 | Thunderbolts |
| YPS | 39 |
v
| 13 | The Saints |
| 07 December 2021 |
| Tyldesley Ladies NC | 27 |
v
| 23 | Tyldesley Tornadoes |
| Tyldesley Tigers | 26 |
v
| 25 | YPS |
| 08 December 2021 |
| Smithills Sports Centre | 24 |
v
| 8 | The Saints |
| Thunderbolts | 31 |
v
| 27 | Rivington Mavs A |
| 04 January 2022 |
| DB3 | 36 |
v
| 26 | Rivington Mavs A |
| Smithills Sports Centre | 28 |
v
| 24 | Tyldesley Tornadoes |
| The Saints | 0 |
v
| 5 | Tyldesley Tigers |
| Thunderbolts | 22 |
v
| 26 | Tyldesley Ladies NC |
| 11 January 2022 |
| Rivington Mavs A | 29 |
v
| 18 | Smithills Sports Centre |
| The Saints | 9 |
v
| 41 | DB3 |
| YPS | 32 |
v
| 21 | Tyldesley Ladies NC |
| 12 January 2022 |
| Tyldesley Tornadoes | 23 |
v
| 20 | Thunderbolts |
| 18 January 2022 |
| DB3 | 34 |
v
| 12 | Smithills Sports Centre |
| Rivington Mavs A | 27 |
v
| 19 | YPS |
| The Saints | 19 |
v
| 30 | Tyldesley Tornadoes |
| 19 January 2022 |
| Thunderbolts | 29 |
v
| 29 | Tyldesley Tigers |
| 25 January 2022 |
| Tyldesley Ladies NC | 0 |
v
| 5 | Smithills Sports Centre |
| Tyldesley Tigers | 0 |
v
| 5 | Rivington Mavs A |
| Tyldesley Tornadoes | 27 |
v
| 40 | DB3 |
| 26 January 2022 |
| YPS | 25 |
v
| 21 | Thunderbolts |
| 01 February 2022 |
| Rivington Mavs A | 35 |
v
| 14 | The Saints |
| Smithills Sports Centre | 16 |
v
| 30 | YPS |
| Thunderbolts | 17 |
v
| 26 | DB3 |
| 02 February 2022 |
| Tyldesley Ladies NC | 0 |
v
| 5 | Tyldesley Tigers |
|
Penalties - Hover over icons for more information
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